Acquired dysfibrinogenaemia masquerading as disseminated intravascular coagulation in acute pancreatitis.

Detection of low molecular weight urokinase in plasma of patient with acute pancreatitis followed by disseminated intravascular coagulation.

It was confirmed by zymographic technique that 1 ml of normal human plasma possessed about 0. 2 IU of urokinase activity which is a high molecular weight form with a molecular weight of 53, 000. Plasma of an acute pancreatitis patient followed by disseminated intravascular coagulation possessed the same amount of urokinase activity as normal plasma, and was confirmed to be composed of two types...

Haematological abnormalities in acute pancreatitis. A prospective study.

Twenty-five patients with acute pancreatitis were studied prospectively in the first week of their admission using haematological and coagulation tests. Platelet counts initially fell and later returned to admission levels. Rising levels of plasma fibrinogen were recorded. The kaolin cephalin clotting time was shorter than its control in twenty-one patients. Eighteen patients had elevated fibri...

Fibrinogen and albumin catabolism in experimental pancreatitis in the rat.

A study of techniques for inducing acute pancreatitis in rats has shown that oil pancreatitis is the most consistent. All methods result in increased fibrinogen catabolism, which is in part due to disseminated intravascular coagulation and in part due to the inflammatory reaction in the pancreas. There is also increased albumin catabolism. Increased fibrin embolization to the lungs results in a...

Disseminated Intravascular Coagulation in a Case of Brucellosis Misdiagnosed as Thrombotic Thrombocytopenia Purpura

Plasma Fibrinogen and D-dimer in Children With Sepsis: A Single-center Experience

Background & Objectives:  In sepsis, enhanced fibrin formation, impaired fibrin degradation, and intravascular fibrin deposition lead to a prothrombotic state. The current study aimed at measuring various coagulation parameters to predict an early marker for disseminated intravascular coagulation (DIC). Methods: The current prospective s...